Endocrine Abstracts

According to the World Health Organisation iron deficiency is the most prevalent form of under-nutrition worldwide. Historically, the causes of iron deficiency were related principally to nutritional deficiencies and this remains a significant factor in many parts of the developing world. However, obesity is also a known cause of iron deficiency and is increasingly correlated with altered iron status and iron deficiency in affected individuals. As the obesity epidemic spreads ...

Previous studies demonstrated that the N-terminal peptide of annexin A1 (AnxA1) (peptide Ac2-26) can mimic the anti-inflammatory actions of the full-length protein in various systems. In the current study, we report the effectiveness of the peptide Ac2-26 as an anti-inflammatory agent in a model of human SGBS adipocytes. We have previously demonstrated that plasma AnxA1 protein is significantly inversely correlated with BMI, body fat level and waist to hip ratio. We have also ...